Saturday, March 31, 2012

Dengue virus turns on mosquito genes that make them hungrier

Friday, March 30, 2012

Researchers at the Johns Hopkins Bloomberg School of Public Health have, for the first time, shown that infection with dengue virus turns on mosquito genes that makes them hungrier and better feeders, and therefore possibly more likely to spread the disease to humans. Specifically, they found that dengue virus infection of the mosquito's salivary gland triggered a response that involved genes of the insect's immune system, feeding behavior and the mosquito's ability to sense odors. The researchers findings are published in the March 29 edition of PLoS Pathogens.

Dengue virus is primarily spread to people by the mosquito Aedes aegypti. Over 2.5 billion people live in areas where dengue fever is endemic. The World Health Organization estimates that there are between 50 million and 100 million dengue infections each year.

"Our study shows that the dengue virus infects mosquito organs, the salivary glands and antennae that are essential for finding and feeding on a human host. This infection induces odorant-binding protein genes, which enable the mosquito to sense odors. The virus may, therefore, facilitate the mosquito's host-seeking ability, and could?at least theoretically?increase transmission efficiency, although we don't fully understand the relationships between feeding efficiency and virus transmission," said George Dimopoulus, PhD, senior author of the study and professor with the Bloomberg School's Malaria Research Institute. "In other words, a hungrier mosquito with a better ability to sense food is more likely to spread dengue virus."

For the study, researchers performed a genome-wide microarray gene expression analysis of dengue-infected mosquitoes. Infection regulated 147 genes with predicted functions in various processes including virus transmission, immunity, blood-feeding and host-seeking. Further analysis of infected mosquitoes showed that silencing, or "switching off," two odorant-binding protein genes resulted in an overall reduction in the mosquito's blood-acquisition capacity from a single host by increasing the time it took the for mosquito to probe for a meal.

"We have, for the first time shown, that a human pathogen can modulate feeding-related genes and behavior of its vector mosquito, and the impact of this on transmission of disease could be significant," said Dimopoulos.

"Dengue virus infection of the Aedes aegypti salivary gland and chemosensory apparatus induces genes that modulate infection and blood-feeding behavior" was written by Shuzhen Sim, Jose L. Ramirez and George Dimopoulos.

###

Johns Hopkins University Bloomberg School of Public Health: http://www.jhsph.edu

Thanks to Johns Hopkins University Bloomberg School of Public Health for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Sunny Health & Fitness Pro Indoor Cycling Bike | Gain Muscle Size

Bodybuilding March 30th, 2012

I recently purchased the Sunny Health & Fitness Pro Indoor Cycling Bike. I?ve utilised it several times and I am just very happy which i went using this type of bike.

I can?t talk about other equivalent priced bikes available on the market ($250-$500 range), but I don?t think you can not work out using this bike if you?re not looking to invest over a new $1000 with a decent spinning bike.

I?m not really a hardcore rewriter, but I?ve gone to enough tuition at different gyms to learn that this bike performs just and also $1000+ ones I?ve made use of at industrial gyms. It?s got the very same feel since those bicycles, and that?s something MY SPOUSE AND I wasn?t guaranteed I?d be in a bike that charge far much less.

Here are some bullet points to the bike:

-Quick supply.

-box was a bit torn within the corners when i received that. I propose opening the idea up and checking in it?s issue. I truly sent back the initial one I received mainly because I sensed bent metal after i reached in the torn hole. However, I thought to open up cost-free one plus discovered that the bent sheet metal was a new ?protective piece? to avoid damage on the front with the bike. Just take care when people open it just in case there may be a problem and you should tape this box ? up ? and post back!

-I?m 5?11? as well as 190 fat and I?d no trouble adjusting the particular seat plus handle bars to get to a relaxed and correct riding situation.

-the wheel spins smoothly plus the resistance will be consistent along with ample. The busting lever works great at the same time. I bought a of our resistance bike a decade ago plus it?s currently dismantled and collecting airborne dirt and dust. If you will be undecided between the two, take it from myself, go considering the ?spin class? type bike! You do not need a calorie or maybe distance counter-top.

if you don?t feel just like you?re being employed or not really sweating, you are going to know it. If you require a coronary heart rate monitor, go with one of the watch kinds?they?re far more accurate than possessing a cardiovascular exercise machine?s handlebars to get a reading.

Overall, 5 beyond 5 with this bike. I?m sure more costly ones have more possibilities or gadgets that will be useful for that hardcore spinners, but in case you are like myself and in spinning however don?t need the extras and the added cost to receive them, then select this bike.

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NAR: Low Real Estate Prices, Desire for Family Retreat Propel ...

AUSTIN, Texas, March 29, 2012 /PRNewswire/ ? In a sign of an emerging recovery in the real estate market, sales of vacation homes in 2011 reached a four-year high, powered by the lowest median sales price in eight years, low mortgage rates, and the desire for a family retreat, according to proprietary research commissioned by HomeAway, Inc. as part of the National Association of Realtor?s (NAR) 2012 Investment and Vacation Home Buyers Survey?.

The research found 33 percent of vacation home buyers purchased a vacation property last year primarily because of low real estate prices, while another 30 percent cited the desire for a family retreat. And 2011 proved an opportune time to buy, according to the NAR survey, with the median sales prices for vacation properties at $121,300, putting ownership within greater reach of more consumers.

Other vacation home buyers cited the following factors as the most important reason to take the plunge into vacation home ownership last year, according to HomeAway? research:

  • Low mortgage rates (13%)
  • For future retirement (11%)
  • Potential for price appreciation (8%)
  • Other (5%)

?The purchase of vacation homes is moving back into the mainstream for a greater number of Americans who are attracted by low prices, rental income potential, and use as a retreat for busy families to get together every year,? says Brian Sharples, chief executive officer of HomeAway. ?Although sales of vacation homes are not as high as historic levels, they are clearly showing signs of a sustained recovery.?

According to the NAR survey, 82 percent of buyers believe now is a good time to purchase real estate, and 39 percent say they are somewhat or very likely to buy vacation property within the next two years.

Vacation Home Owners Believe Rental Income Can Help Offset Mortgage on Second Home

Nearly all (91%) vacation home buyers say they plan to rent their property within the next 12 months to either long-term or short-term renters or a combination of the two. Of those buyers, 71 percent cited rental income potential as a factor in their purchase decision and nearly three-quarters (74.5%) of buyers believe they will make enough rental income to cover at least half of their mortgage.

According to Sharples, HomeAway research conducted in Q4 of 2011 of 4,905 owners listing their vacation homes on HomeAway?s U.S. sites show that 70 percent generate enough rental income to cover half or more of their mortgage, and 51 percent cover at least three-fourths of their mortgage.

Of those buyers intending to rent their property, about 40 percent plan to make their vacation homes available for rent between one and eight weeks over the course of the next year; 32 percent plan to rent their properties between nine and 26 weeks per year; and 27 percent plan to rent their homes between 27 and 52 weeks per year.

Vacation home buyers are willing to rent their property to more than one type of guest. The majority (70%) of people who plan to rent their property to short-term renters say they?ll rent the home to vacationers, while 37 percent plan to rent to business travelers and 24 percent plan to rent to other tenants, such as college students or people relocating to the area.

By the Numbers:

Highlights from the NAR 2012 Investment and Vacation Home Buyers Survey

?

502,000 ? Number of vacation homes sold in 2011 $121,300 ? The median sales price of a vacation home in 2011, down 19% from 2010
38 ? Percentage of vacation home buyers under the age of 45 $88,600 ? Median household income of vacation home buyers
42 ? Percentage of vacation home buyers who paid cash for their property
69 ? Percentage of vacation home buyers who plan to own their property more than six years
33 ? Percentage of vacation home buyers saying they are very or somewhat likely to buy another property within the next two years

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PFT: Ricky Williams might unretire to be a Charger

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The Bills? website has a sneak peek of the new New Era hats.

Dolphins OL Vernon Carey kicked in $20,000 for new equipment at his Miami-area high school?s weight room.

Bill Belichick?s daughter is an assistant lacrosse coach at Ohio State.

Will Hill, a former Tim Tebow teammate at Florida, has a prediction:? ?Knowing him, being with the Jets, I know he wants to be that starting guy.? I know that he?s going to pull others to him.? It?s going to be a big change for the Jets.?

Tottenham and Liverpool of the Barclays Premier League will be playing the other kind of football at the Ravens? stadium in July.

With training camp now moved to Paul Brown Stadium, the Bengals are trying to schedule open practices that won?t conflict with Reds games.

Bernie Kosar looks at the Browns? options with the fourth pick in the draft.

The Steelers remain interested in bringing back WR Jerricho Cotchery, who most recently visited the Rams.

Texans defensive coordinator Wade Phillips has taken to Twitter, with the handle @sonofbum.

A company making Andrew Luck Colts jerseys will likely soon feel the wrath of Nike.

Jags owner Shahid Khan should make his foray into personnel decisions a one-shot deal.

Though the Titans may have signed G Steve Hutchinson as Peyton bait, QB Matthew Hasselbeck is happy to be reunited with his former Seattle teammate.

Rams coach Jeff Fisher addressed the challenge of facing Broncos QB Peyton Manning:? ?We?ve always said it?s like preparing for one of those quarterbacks in a video game.? You just can?t fool him.? He?ll move fast and get the ball to the right people.?

Chiefs S Eric Berry says it?s easier to rehab his torn ACL because he?s got company.

New Raiders RB Mike Goodson says he?s fully recovered from a hamstring injury suffered during the 2011 season.

The Chargers still have offers on the table for DL Luis Castillo and RB Jacob Hester.

NBC?s Al Michaels explains the attraction of the 8-8 Cowboys to start the 2012 season:? ?There may be as many people out there who watch to see the Cowboys lose as watch to see them win.?

The suspension of Giants RB Andre Brown makes it even more important that the other guys on the depth chart behind Ahmad Bradshaw step up.

Analysts like Brian Baldinger and Ron Jaworski believe that the loss of Jason Peters will hurt the Eagles badly.

Former NFL quarterback Jake Plummer, who once played for Mike Shanahan, agrees with Donovan McNabb regarding RG3?s fit in D.C.

A fan recently approached Bears chairman George McCaskey and simply said, ?My parents have been ticket holders since 1932.? Get it right.?

Lions G.M. Martin Mayhew strongly favors a 90-man training-camp roster.

Packers coach Mike McCarthy wants more competition on defense.

The Vikings plan to bring Andrew Luck and Robert Griffin III to town for pre-draft visits.

Falcons coach Mike Smith says the team was ?very inconsistent? in 2011.

Panthers coach Ron Rivera doesn?t think that TE Jeremy Shockey was the Saints? whistleblower, but that even if he were it wouldn?t change the team?s interest in bringing him back.? (The NFL?s lawyers approve of this message.)

Saints coach Sean Payton?s appeal, even if unsuccessful, also could mean that he?ll lose less salary.

The Bucs will pay CB Ronde Barber $3 million in 2012, down 25 percent from 2011.

Cardinals RB Beanie Wells threw out the first pitch at a spring-training game involving the two teams from his home state of Ohio.

The Rams had considered using the transition tag on P Donnie Jones.

49ers RB Frank Gore has been helping RB Lamar Miller get ready for the draft.

The Seahawks? new Nike-designed alternate jersey is expected to be gray.

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Mashable Photo Challenge Results: What's In Your Laptop Bag?

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Posts from Shopping-and-Product-Reviews:Collectible-Jewelry ...

How Many Wrist Watches Do You Think There Are?

By Anonymous on Mar 27, 2012 03:38 pm

I recently began an internet business selling watches, and while studying my niche market, I was overwhelmed at the vast range of styles and brands available. I have been pre-occupied with thinking about how big the market the market is - how many watches there are in our universe.
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All You Must Know About Unique Rings for Women

By Anonymous on Mar 26, 2012 05:56 pm

Unique rings for women are the modern world innovation which provides you with lots of pretty designs and styles in rings. They hold a great importance in every individual's life, as it is given on engagement ceremony or wedding ceremony, depending on the religion. In different religions there are varied timings of giving rings to the partner, in some religions it is given to the women on the wedding day whereas in other religions, they are given on engagement day.
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All You Must Know About Silver Rings for Men

By Anonymous on Mar 26, 2012 05:55 pm

Silver rings for men are quite popular as people want different things, but not the old styles. Today, people prefer silver rings instead of gold rings. Gold is now available in different colors like white, pink, copper etc.
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Exploring the Top Ten Categories of Israeli Jewelry

By Anonymous on Mar 26, 2012 01:49 pm

We venture to explore the top ten categories of Israeli jewelry. We will also be looking at the criteria we use to arrive at the respective categories. This information should be useful to anyone considering buying jewelry from Israel. It should also be useful to anyone considering starting to deal in Jewelry from Israel (or jewelry designed by Israelis in the Diaspora). Further, it should be useful to anyone thinking of becoming a commentator on Jewish jewelry.
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Cartier Love Charity Bracelet

By Anonymous on Mar 26, 2012 08:34 am

Cartier is one of the best known and longest established makers of fine jewellery in the world. The famous French designer has been coming up with new and innovative designs for many years and is considered to be at the leading edge of the industry. Not content with being the market leader, Cartier have become more socially aware and are becoming increasingly more involved in charities across the globe.
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Phosphosiderite - A Rare Gemstone - Its Characteristics and Properties

By Anonymous on Mar 23, 2012 06:20 pm

This article talks in detail about Phosphosiderite gemstone. It includes details on its color, origin, basic characteristics and its properties.
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How To Take Care Of Your Bone Bracelets When Not In Use

By Anonymous on Mar 23, 2012 04:28 pm

Bone bracelets are handcrafted by skilled men and women with the inspiration of the culture of the past. These are buried treasures that can be worn by people of all ages as fashion accessories.
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Choosing Body Jewellery - Which Metals Are Safe for Piercings?

By Anonymous on Mar 23, 2012 12:43 pm

Body jewellery has the ability to give an eye-catching, stunning and unique look. But whether you are looking at nose studs, labret studs or more exotic body jewellery, safety should be a priority. Cheap throwaway jewellery can irritate the skin, harbour bacteria and even release harmful impurities into the bloodstream. It is important to understand which metals are safe for your body jewellery.
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Pandora Style Charm Beads: The Advantages That They Offer

By Anonymous on Mar 23, 2012 12:29 pm

There has been a huge increase in the number of people who are making charm bracelets over the last few years. The main reason for this is the introduction of Pandora bracelets. They greatly simplify the process of making them and allow you to change the design anytime that you want. These along with their other advantages have made them hugely popular.
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Tips On How To Purchase Quality Glass Beads

By Anonymous on Mar 23, 2012 10:55 am

Most of the glass beads available today are handmade. It is believed that the first glass beads were made 9000 years ago. In those days, they were used not only in jewelry making, but they were also equivalent to money and traded for things. Beads made of glass can be found in many different colors, sizes, shapes and finishes.
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Save Money and Buy Your Beads in Bulk

By Anonymous on Mar 23, 2012 08:32 am

Beads are certainly beautiful, but let's face it. They can sure be expensive! There are places you can shop online for beads bulk. It doesn't matter the style of bead you prefer, you can probably find it in bulk from one of the huge bead warehouses.
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What Are Pandora Style Beads?

By Anonymous on Mar 22, 2012 06:24 pm

Over the last few years Pandora style bracelets have become very popular, that being said there are a lot of people who really don't know what they are. While it would not be fair to give them all of the credit for the massive increase in popularity in charm bracelets over the last few years there is no getting around the fact that they are a major contributor. They offer a lot of advantages over the way that things were done in the past.
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Some Things To Know About The Lampwork Beads

By Anonymous on Mar 22, 2012 05:25 pm

There was a time when glass was not part of everyday life. But when glass started being made, it used to be a carefully guarded secret. The technique of making glass was only passed on from fathers to their sons.
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How To Buy Quality Lampwork Beads?

By Anonymous on Mar 22, 2012 05:25 pm

For a jewelry maker, it is always essential to buy quality jewelry making supplies such as jewelry tools, beads and wires and equipment. Lampwork beads are made from glass and this means that they have greater chances of breaking or splitting compared to other types of beads used in jewelry making.
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Types of Watches for Men

By Anonymous on Mar 22, 2012 01:59 pm

Watches are for men as pearl necklaces are for women. They are a must-have accessory that is not only fashionable, but also functional. There are hundreds of different accessories for women, but not many men can't get away with a diamond ring, so the right watch might be the way to go.
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Jewellery That Lets You Create A Number Of Different Looks

By Anonymous on Mar 22, 2012 12:11 pm

The way that Nomination charm bracelets differ from other bracelets is that with traditional bracelets, charms will attach on the bracelets whereas the Nomination charms connect together to make the bracelet- they just clip in. Nomination bracelets can be begun by a starter bracelet which are made-up of lots of simple links connected together that are then replaced by the charms as you progressively buy them (this means that you don't have to purchase all your desired charms at once!).
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Jewellery That Can Be Suitable For A Range Of Different Occasions

By Anonymous on Mar 22, 2012 12:04 pm

Many people aim to look really individual and unique when it comes to what jewellery they're wearing - this is why they choose to wear Thomas Sabo charms. They are made to a really high quality and the recognised brand even has celebrities as fans! Celebrities constantly have to ensure that they look good and are always in the public eye so must ensure that they are wearing decent quality products such as Thomas Sabo charms.
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Picking Jewellery To Reflect Your Personality

By Anonymous on Mar 22, 2012 12:02 pm

It's common for people to spend a lot of time trying to find the perfect types of jewellery for them as there is a wide range of different types on the market. One of the main things that people are concerned about when it comes to jewellery is the quality. It's important for people to find jewellery that will stay in great condition for a long time and still look like new!
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Looking To Buy A Key Chain? Here Are Some Of The Many Types To Choose From

By Anonymous on Mar 22, 2012 11:33 am

A key chain is a small chain that is usually made of plastic or metal and is attached to a keyring. Key chains are functional and practical items for anyone to use. The main function is to help secure keys.
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Why Are Some Fountain Pens Just Plain Interesting?

By Anonymous on Mar 21, 2012 09:28 am

Engravers Script is one of the writing styles that I have been trying to learn, so the Pilot Custom 742 with a Falcon nib seemed to be the ideal pen. I have several Pilot pens so I knew the quality and finish would be good and I wasn't disappointed.
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Chrysocolla Gemstone - Meaning, Origin, Healing Properties, Uses, Similarities and Care

By Anonymous on Mar 21, 2012 09:02 am

This article talks about Chrysocolla gemstone. It provides information on the formation of the stone, healing properties, uses and care details in brief.
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Source: http://wedding-dresses-womens-clothes-online.blogspot.com/2012/03/posts-from-shopping-and-product_28.html

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Health Tip: Warning Signs of Gum Disease

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Source: http://news.yahoo.com/health-tip-warning-signs-gum-disease-110206587.html

richard cordray shannon de lima joe torre west virginia university michele bachmann jessica biel tim howard

Hammerhead shark twin discovery creates concern for species

The scalloped hammerhead shark has a twin, scientists have discovered. And that discovery may show that scalloped hammerheads are rarer than first thought.

Scientists recently confirmed that endangered scalloped hammerhead sharks have a fishy twin ? a newfound species, still unnamed, that is distinct, yet very closely resembles the threatened sharks.

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The case of mistaken identity indicates that scalloped hammerhead sharks?are even more scarce than once thought, according to some researchers.

Since it's very hard to tell the two species apart ? only differences in their DNA and number of vertebrae reveal their true identities ? it's likely that previous assessments of scalloped hammerhead sharks exaggerated their numbers because the counts likely included the look-alike sharks.

"It's a classic case of long-standing species misidentification that not only casts further uncertainty on the status of the real scalloped hammerhead, but also raises concerns about the population status of this new species," Nova Southeastern University Oceanographic Center professor Mahmood Shivji said in a statement.

Shivji's team at the Florida university first discovered the new hammerhead species in 2005 when examining the DNA of sharks thought to be scalloped hammerheads based on their physical appearance. A research team from the University of South Carolina independently confirmed the existence of the new species in 2006.

Combined genetic assessments from both institutions show that at least 7 percent of the sharks in U.S. waters originally thought to be scalloped hammerheads turned out to be the newly identified species.?

Now, researchers have found the unnamed shark, a so-called "cryptic" species, swimming in waters off the coast of Brazil, thousands of miles from where the species was initially discovered. The find indicates the cryptic species is widespread, and may be facing similar pressure as its nearly identical cousin.

Shark populations around the world have declined precipitously in recent decades, with millions of the iconic fish falling victim to the grisly practice of finning.

Shark fins fetch a high price in China, where they are used for shark fin soup.

Shark finning is largely banned in the United States, and many individual states have banned the trade and possession of shark fins. However, evidence from around the world indicates that finning continues to claim millions of shark lives each year.

Follow OurAmazingPlanet for the latest in Earth science and exploration news on Twitter @OAPlanet and on Facebook.

Source: http://rss.csmonitor.com/~r/feeds/science/~3/U4ESl2qNUhw/Hammerhead-shark-twin-discovery-creates-concern-for-species

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New Images of Titanic Wreck Revealed

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